Endoglin anticorps (AA 26-176)
Aperçu rapide pour Endoglin anticorps (AA 26-176) (ABIN372489)
Antigène
Voir toutes Endoglin (ENG) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 26-176
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Réactivité croisée (Details)
- Species reactivity (tested):Human.
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Purification
- Immunoaffinity Chromatography
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Immunogène
- Recombinant protein encoding amino acids 26-176 of Human CD105.
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Isotype
- IgG
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Indications d'application
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ELISA. Immunohistochemistry on Paraffin Sections: (1/100).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.1 mg/mL
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Buffer
- 10 mM PBS, pH 7.6 containing 0.2 % BSA as stabilizer and 15 mM Sodium Azide as preservative, before the addition of Glycerol to 40 %
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- Endoglin (ENG)
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Autre désignation
- CD105 / Endoglin
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Sujet
- CD105 or Endoglin is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. It exists on an O- and N-glycosylated homodimer. Up regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation associated endothelial marker. CD105 binds to TGF beta 1 and 3 with high affinity but not to TGF beta 2.Synonyms: END, ENG, HHT1, ORW, ORW1
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ID gène
- 9606
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UniProt
- P17813
Antigène
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